The Gasch Lab at the University of Wisconsin-Madison seeks an ambitious postdoctoral fellow to investigate RNA life cycles from birth to death in wild yeast strains.
The project emerged from a study of aneuploidy tolerance in wild yeast, in which we identified an RNA binding protein that enables wild yeast to tolerate extra chromosomes. Goals of current work include understanding how this and other RNA binding proteins regulate mRNA life cycles from birth to death, and how this regulation enables aneuploidy tolerance. The project combines yeast genetics and genomics including RNA-seq, RIP (RNA-immunoprecipitation)-seq and other methods, mass-spec proteomics, and single-molecule RNA fluorescence in situ hybridization (smFISH). The ideal candidate will have wet-bench experience in genetics, genomics, microbiology, molecular biology, or related fields. Past experience generating and analyzing large datasets is a plus but not required; candidates that lack this experience should have a strong desire to hone their skills in this area.
Candidates should have:
- Been recently awarded or soon to be awarded a Ph.D. in genetics, biochemistry, molecular biology, microbiology, or similar field.
- Demonstrated productivity through first author publications or preprints
- Be highly motivated, independent, and driven
- Be interested in joining a collaborative research group in the Gasch Lab
The Gasch Lab is housed within the Laboratory of Genetics at the University of Wisconsin-Madison and the new Center for Genomic Science Innovation (of which Dr. Gasch is the Interim Director). UW-Madison is a vibrant community with a strong culture of interdisciplinary collaboration and communication. There are many opportunities for research and professional development. Madison is an exceptional place to live and is frequently voted one of the best cities in the country.
Intersted candidates should email a CV, statement of research interests, manuscript preprints (if yet to be published), and contact information for three references to Audrey Gasch (firstname.lastname@example.org).
We welcome and encourage women, members of underrepresented minority groups, and individuals with disabilities to apply.